Why San Francisco 49ers changed their uniform for NFL Week 5 game against Arizona Cardinals Sunday, and why it's not the ...

The 49ers get their bye in before that game, so holding McCaffrey out for two more contests after next week would give him another seven days of rest. For now, Jordan Mason will lead the way as San ...

We’re now five weeks into the NFL season, and there are far more questions than answers for the San Francisco 49ers.

As the San Francisco 49ers gear up for another run at a Super Bowl title, they find themselves with some unexpected holes to fill. All season, the 49ers' roster has been decimated by injuries ...

Looking at Thursday’s San Francisco 49ers at Seattle Seahawks Week 6 NFL odds, lines and trends. Here’s what you need to know ...

The San Francisco 49ers (2-2) are solid favorites -- expected to win by at least a touchdown (currently -7.5) -- versus the Arizona Cardinals (1-3) in a matchup of two division rivals. The game ...

As the San Francisco 49ers gear up for their 2024 season opener against the New York Jets on Monday Night Football, the team is hoping that the sting of losing the Super Bowl last season will ...

The 49ers just blew another 10-point fourth quarter lead and lost 24-23 to the Arizona Cardinals. Now the 49ers are 2-3. Here are their grades fo ...

Anyone trekking from Sacramento to the Bay Area on Sunday to watch the San Francisco 49ers would be mistaken for thinking they brought the heat along for the ride. Such is the setting for what’s ...

Despite a 25-22 Super Bowl LVIII loss to the Kansas City Chiefs, the San Francisco 49ers are already a favorite ... below to head directly to the NFL Fan Shop page on Amazon and select your ...

McBride has 14 catches for 122 yards so far this season. On Sunday in San Francisco (Santa Clara), record heat for early October is expected. With a projected high of 95, the 49ers wanted to switch ...